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Sioux Biochemical – SBEDGE®​

About Us

Type 2 Collagen Supplement Manufacturer

Sioux Biochemical, Inc. specializes in the extraction and purification of proteins and biomolecules and specifically manufactures bovine collagen supplements for improved health.

We have developed a technologically advanced product called COLLAGEN NATIVE TYPE 2 (CNT2) under the SBEDGE® name. This product was developed to promote joint and cartilage health and can also assist in promoting gut, skin, heart and lung health when taken orally.

COLLAGEN NATIVE TYPE 2 can help restore and rebuild the collagen that the body loses due to aging to help renew and restore what you have lost.

Our History

Founded in 1995 by Allan Kramer, Ph.D., our team of experts in protein chemistry have more than 27 years of experience in isolating proteins for research and manufacturing the highest quality dietary ingredients for joint health.

In addition to utilizing our experience and innovation for internal manufacturing interests, we also offer our contract processing services to the greater biotechnology sector.

David Kramer with Type 2 Collagen Drums
Dr Kramer QC Lab

Our Core Foundation

The different types of collagens interact with your body in different ways; (Read: “Different Types of Collagen”).  This is particularly true of Native or ‘undenatured’ collagen sources.  Since Type 2 collagen helps to form the cartilage that make up your joints, it’s no wonder that this type of collagen is often known for supporting joint health.

Sioux Bio Manufacturing Web

Sioux Biochemical, Inc. is committed to cGMP principles at all levels of the organization and applies these principles as required by the unique characteristics of each product line. This refers to the Current Good Manufacturing Practice regulations that are enforced by the Food & Drug Administration (FDA) that specify systems that ensure the proper design, monitoring and control of manufacturing processes and facilities.

We have developed and maintain a Quality Management System (QMS) that controls every step of the process, from Facility Design, Equipment Commission, and Supply Chain Management through Manufacturing to release only high-quality products to you.

Products and services are developed, implemented, and released to meet or exceed the requirements of our customers – whether it be a retail consumer, industry partner, or service contractor.

Take the 90-day Challenge!

See how Native Type 2 Collagen will help to resupply your body with natural collagen to rebuild the tissues that are damaged and are causing joint pain!

We are Proud to be Made in America!

SBEDGE® – Type 2 Collagen Supplements

Although there are a variety of collagen types, Type 2 Collagen is the major type found in cartilage which is known for supporting healthy joints.

In addition to being the connective tissue that protects the ends of longer bones at the joints, cartilage is also a structural component of the rib cage, ear, nose, bronchial tubes, spine and hip.

Our Collagen is 100% sourced from North American, USDA inspected, bovine sources and is processed in the great state of Iowa in the United States.